Comparing multiple treatments 1: Overview or intervention review?

Topic category Other methods for preparing systematic reviews
Date and Location
Date: 
Monday 1 October 2012 - 13:30 - 15:00
Location: 
Methods Group
Methods Group: 
Comparing Multiple Interventions Methods Group
Contact persons and facilitators
Contact person Affiliation Country
Lorne Becker (Contact this person) SUNY Upstate Medical University USA
Facilitator Affiliation Country
Lorne Becker SUNY Upstate Medical University USA
Tianjing Li US Cochrane Center, Cochrane Eyes and Vision Group USA
Deborah Caldwell Univeristy of Bristol United Kingdom
Other contributors
First nameLast nameAffiliation and Country
First name: 
Deborah
Last name: 
Caldwell
Affiliation and Country: 
University of Bristol, United Kingdom
Target audience
Target audience: 
Authors, Managing Editors, Co-ordinating Editors
Is your workshop restricted to a specific audience or open to all Colloquium participants?: 
Open
Level of knowledge required: 
Any
Type of workshop
Type of workshop: 
Training
Abstract text
Abstract: 
Objectives:
• To introduce key issues in the use of indirect comparisons in Cochrane reviews, including the identification of an appropriate question, the construction of a network map, and the decision of whether an intervention review or an overview is the better format.
• To discuss methodological considerations when undertaking such reviews.

Description:
Indirect comparisons can be useful in the synthesis of evidence on comparative effectiveness, particularly when the evidence from head-to-head trials is lacking or insufficient. A variety of methods are available, ranging from simple narrative methods to formal network meta-analysis.

This is the first of two related workshops. It will focus on non-statistical aspects and will draw upon the results of a special meeting on this topic organized by the Comparing Multiple Interventions Methods Group in April 2012. We will introduce the concept of indirect comparison and describe the construction of a network of interventions. We will discuss appropriate questions for a review involving indirect comparisons and present a roadmap for deciding whether an intervention review or overview fits best. Lastly, we will discuss methodological considerations when undertaking such reviews.

We will encourage participants to share their experiences and perspectives on this rapidly developing area of methodology.